THE CR WAY^™ — A JOYOUS LIFESTYLE

Healthy Start Membership — Free!

Find out more about how the world’s healthiest, happiest lifestyle can make a positive difference in your life.

Gain full access to:

Enjoy introductions to:

Happy Dieting
Getting Smarter
Long, Healthy Life
Delicious Food
A Happier You

BECOME A HEALTHY-START MEMBER

Full Memberships Support Longevity Research
Choose a plan that achieves your goals:

Optimal Health

Healthful Weight Loss

Diabetes Prevention and Intervention

Brain Booster

Longevity Level

Easy Comparison of Membership Costs and Benefits

Enjoy life-transforming benefits offering the best chance of living longer and better!

Expert Guidance – Live Teleconferences

Most experts charge hundreds of dollars for teleconferences, which are included in all full memberships. Join renowned leaders of calorie restriction and longevity science and leading experts – live on twice-monthly teleconferences where you can ask the questions you need.

Advanced Dietary Software

Optimal Health, Healthful Weight Loss, Diabetes Intervention, and Brain Booster Memberships include the NutriBase CR Way Edition Software, the advanced diet and lifestyle manager that downloads in minutes to your desktop or laptop computer. Delicious recipes and foods to choose come preloaded.

Use it to help activate your longevity biochemistry as well as improve your heart health, prevent or fight major diseases, lower blood sugar, manage exercise, make it easy to lose weight, and even improve your mood.

Quick-start guide speeds you on your way happily

You get online access to The CR Way™ to Happy Dieting, which shows you how to use your food and lifestyle to increase happiness, making a healthful diet satisfying to follow – and fun! Healthful Weight Loss and Brain Booster members receive the guide as a download.

Using the quick-start guide lowers your stress and helps you avoid disease, too. This resource even offers a CR Way to Fast Foods Meal Plan for busy people who have no time to fix food but don’t want to sacrifice their health.

Full access to groundbreaking content on LivingTheCRWay.com

Delicious Food

Delicious, healthful recipes to savor

The CR Way To Peak Performance

Your diet and lifestyle coach for performing at your best

Getting Smarter

A blueprint for improving brain power

Long, Healthy Life

Introduction to the beneficial cellular changes that are fundamental to living the CR Way.

A Happier You

Strategies to relieve stress and increase happiness

Protection From Disease

Help in preventing or fighting Alzheimer's Disease, Arthritis, Cancer, Diabetes, Hearing Loss, Heart Disease, Kidney Disease, Migraines Headaches, Macular Degeneration, Muscle Weakness (sarcopenia), Obesity, Osteoporosis, Parkinson's Disease, as well as strategies to boost the Immune System.

Science Behind The Benefits

Description of the fundamental science that supports (and explains) the benefits

The Longevity Guide

Pointers for becoming a centenarian

Begin your journey to a longer, healthier life!

The Nutribase CR Way Edition Software turns your home computer into the world’s leading authority on health and longevity! The software’s extensive tracking capabilities eliminate guesswork that leads to unhealthful outcomes. It’s easy to track weight as well as calorie and nutrient intake -- including fatty acids and phytochemicals. You can also track exercise, glucose levels, heart health, and even happiness level -- which may be a key determinant of longevity.

If you need to lose weight, you can enter your weight-loss goals into the software, and it will calculate a healthful number of pounds to lose each week as well as the appropriate calorie intake to achieve your goal. The software comes loaded with recipes that increase your happiness level, empowering you to leave unhealthful comfort foods behind. The software is included as part of the benefits of the Optimal Health, Healthful Weight Loss and Brain Booster Memberships.

PURCHASE software

Calorie restriction science is the foundation for many CR Way recommendations.Meredith Averill, coauthor of The CR Way, is chairman of the Board of The CR Society International.org. Paul McGlothin, coauthor of the CR Way is its vice president of research. We do everything we can to help people apply CR science to their lives in a way that is healthful, fun, supportive and delicious!

When we speak of calorie restriction, we are really talking about a lifestyle that creates a metabolic shift away from growth to efficient cell maintenance and from energy usage to energy production. You can find out more about our take on that in a presentation we made to scientists and medical professionals at UCSF. Calorie restriction science began with Dr. Clive McKay who showed that limiting calories can extend lifespan.¹

¹ McCay CM, Crowell MF, Maynard LA. 1935. The effect of retarded growth upon the length of the life span and upon the ultimate body size. J. Nutr. 10:63-79

Important Breakthroughs

Insulin IGF-I

In 1992, Cynthia Kenyon identified the daf-2 pathway, which is similar in function to the insulin/IGF-1 pathway in humans, as an aging regulator in Caenorhabditis elegans. Changes in the daf-2 gene resulted in doubling the lifespan of the nematodes.³

Subsequentstudies have confirmed the importance of the insulin/IGF-I pathway for regulating aging in a wide spectrum of species including humans.⁴

³Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1 993 Dec 2;366(6454):461-4 PMID: 8247153

⁴Barbieri M, Bonafè M, Franceschi C, Paolisso G. Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab. 2003 Nov;285(5):E1064-71. PMID: 14534077

Downregulation of the Insulin/IGF-I-1 pathway is a major focus of the CR Way

A related pathway that has attracted lots of attention is the mTOR (Mammalian target of Rapamycin, an enzymatic complex that is made quiescent by rapamycin, a pharmaceutical. mTOR is a down regulation target of the CR Way lifestyle.mTOR is a major regulator of anabolic pathways.Lives of many species can be extended by knocking out mTOR signaling:

Hansen, M. et al. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95–110 (2007). PMID: 17266679

Human Calorie Restriction

Roy L. Walford, M.D., focused his scientific work on the biology of aging and was chief medical officer of the Biosphere 2 experiment that became a two-year study in human calorie restriction.¹¹Walford excelled in many other fields of endeavor and was the first to popularize calorie restriction (see http://walford.com/bio.htm) by writing several books on how humans can practice CR Walford’s colorful career and the mammalian work by Mark Lane, Rick Weindruch (Walford’s former student), and others attracted media attention. ¹² Soon a populist CR movement emerged, led by Brian M. Delaney, who created an Internet discussion group that developed into the CR Society Intl. (see www.CalorieRestriction.org/History).

¹¹Walford RL, Weber L, Panov S. Caloric restriction and aging as viewed from Biosphere 2. Receptor. 1995 Spring;5(1):29-33. Review. PMID: 7613481

¹²Wade N. Study Spurs Hope of Finding Way to Increase Human Life. New York Times. August 25, 2003

Calorie restriction science and practice are changing. They no longer emphasize only limiting calories but also focus on activating the regulators that control aging. To help people apply the latest research to live healthier, longer lives the CR Way offers an innovative approach that integrates a nutrient-dense, low-calorie diet into a lifestyle that includes meditation, yoga, exercise, support and friendship that improve quality of life. The CR Way members are encouraged to choose programs that fit their needs and lifestyle.

Subsequent studies have confirmed the important of the insulin/IGF-I pathway for regulating aging in a wide spectrum of species including humans.⁴

Healthy Start Membership — Free!

Full Memberships Support Longevity Research Choose a plan that achieves your goals:

Optimal Health Healthful Weight Loss Diabetes Prevention and Intervention Brain Booster Longevity Level Easy Comparison of Membership Costs and Benefits

Easy Comparison of Membership Costs and Benefits

Full Memberships Support Longevity Research
Choose a plan that achieves your goals:

Optimal Health

Healthful Weight Loss

Diabetes Prevention and Intervention

Brain Booster

Longevity Level

Easy Comparison of Membership Costs and Benefits